Tuberculosis in Children: Epidemio-Clinical Aspects in the Paediatric Department of the Gabriel Touré University Hospital Center

Introduction: Globally, tuberculosis is the leading cause of death from a single infectious agent ahead HIV/AIDS. Approximately 10 million people contracted TB in 2017, 10% whom were children aged 0 - 15 years, or about 1 with 250,000 deaths 2016 (including HIV-associated TB). The signs are not always specific and diagnosis remains difficult unlike adults. According to study conducted 2011 paediatric department CHU-Gabriel Touré, only seventeen cases all forms found, approximately 0.2% hospitalised children. objective our was investigate epidemiological clinical aspects Materials method: This prospective, cross-sectional descriptive that took place 24 October 2017 23 2018, 12 months 0-15 years. Data collected an individual medical record opened for each patient survey form established child. Results: During period, 40,434 consulted. Tuberculosis suspected 91 children, frequency 0.22%. age range 4 years 36.3% median 72 months. sex ratio 1.8. Chronic cough 84.6% malnutrition 24.17% most frequent symptoms. Chest X-ray revealed bilateral pulmonary lesions 52.7% mediastinal adenopathy 12.1%. TST positive 10.9% patients, microscopy 26.4%, Gene Xpert 18.7%, culture 16.5%. biological retained 48.4% represented 93.2%. therapeutic regime (2RHZE/4RH) used 81.6% evolution favourable 65.9% patients. Conclusion: context. specific, further studies needed elucidate this disease.